Epidermal Growth Factor Receptor-Coding Sequence Exon-Regulatory Sequence-Critical Advances

Exon 8 amplification of epidermal growth factor receptor (EGFR) in invasive breast carcinomas

Conclusions: It appears that amplification of the coding sequence exon 8 exhibits similar biological behaviour to amplification of the regulatory sequence in intron 1, leading to elevated levels of EGFR protein.© 2012 Blackwell Publishing Ltd (Source: Histopathology) read more..

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Plenary Session: 4 Critical Advances in OncologyPlenary Session: 4 Critical Advances in Oncology

Dr. Kathy Miller previews the ASCO plenary session studies in breast cancer, prostate cancer, lymphoma, and oligodendroglioma, all 4 of which signal significant advances in science and treatment. Medscape Hematology-Oncology (Source: Medscape Hematology-Oncology Headlines) read more..

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More Genes Discovered In The Fight Against Breast Cancer

In a study published in Nature, researchers describe nine new genes that drive the development of breast cancer. This takes the tally of all genes associated with breast cancer development to 40. The team examined all the genes in the genomes of 100 cases of breast cancer... read more..

source:http://www.medicalnewstoday.com

Human Epidermal Growth Factor Receptor 2-Immunohistochemical-Breast Cancer Cells

BOND™ ORACLE™ Human Epidermal Growth Factor Receptor 2 (HER2) Immunohistochemical (IHC) System

The BOND™ ORACLE™ Human Epidermal Growth Factor Receptor 2 (HER2) Immunohistochemical (IHC) System is a laboratory test that measures how much HER2 protein is being made by breast cancer cells. The test uses a technique that will specifically recognize.. (Approved: 4/13/2012) (Source: Medical Device Approvals) read more..

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Epidermal Growth Factor Receptor-Consumer Information-Immunohistochemical-Breast Cancer Cells

Consumer Information on: BOND? ORACLE? Human Epidermal Growth Factor Receptor 2 (HER2) Immunohistochemical (IHC) System - P090015

The BOND? ORACLE? Human Epidermal Growth Factor Receptor 2 (HER2) Immunohistochemical (IHC) System is a laboratory test that measures how much HER2 protein is being made by breast cancer cells. The test uses a technique that will specifically recognize.. (Source: Food and Drug Adminstration (FDA): CDRHNew) read more..

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Amplified in breast cancer 1 oncogene enhances human cholangiocarcinoma growth and chemoresistance by simultaneous activation of Akt and Nrf2 pathways

Conclusion: AIB1 plays an important role in proliferation and chemoresistance of CCA through simultaneous activation of Akt and Nrf2 pathways, suggesting that AIB1 is a potential molecular target for CCA treatment. (HEPATOLOGY 2012) (Source: Hepatology) read more..

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